Product Name :
Ras Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
C-BAS/HAS antibody c-H-ras antibody C-HA-RAS1 antibody CTLO antibody GTPase HRas antibody GTPase KRas antibody GTPase NRas antibody H-Ras-1 antibody H-RASIDX antibody Ha-Ras antibody 展开
Function :
Ras superfamily is a protein superfamily of small GTPases, which are all related, to a degree, to the Ras protein subfamily (the key human members of which are KRAS, NRAS, and HRAS). Receptor tyrosine kinases and G protein-coupled receptors activate Ras, which then stimulates the Raf-MEK-MAPK pathway.4-Bromo-7-(trifluoromethyl)quinoline Formula GTPase-activating proteins (GAP) normally facilitate the inactivation of Ras. However, research studies have shown that in 30% of human tumors, point mutations in Ras prevent the GAP-mediated inhibition of this pathway. The most common oncogenic Ras mutation found in tumors is Gly12 to Asp12 (G12D), which prevents Ras inactivation, possibly by increasing the overall rigidity of the protein. This antibody is predicted to react with H-Ras, N-Ras and K-Ras.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Synthetic peptide within Human Ras aa 11-60 / 189.8-Bromo-5-chloroquinoline Price
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IF-Cell, IHC-P, FC
Coupling :
unconjugated
Clone number:
RRID:
AB_3069572
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*PBS (pH7.PMID:33403946 4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 21 kDa
Positive control :
PC12 cell lysate, MCF-7 cell lysate, 293T cell lysate, Mouse brain tissue lysate, Mouse intestine tissue lysate, Rat brain tissue lysate, HCT116, Hela, HepG2, MCF-7, mouse kidney tissue, rat small intestine tissue, human liver cancer tissue, human kidney muscle tissue, mouse kidney tissue, mouse small intestine tissue .