Product Name :
SDHB Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
CWS2 antibody DHSB_HUMAN antibody FLJ92337 antibody Ip antibody Iron sulfur subunit antibody Iron sulfur subunit of complex II antibody Iron-sulfur subunit of complex II antibody mitochondrial antibody PGL 4 antibody PGL4 antibody 展开
Function :
In aerobic respiration reactions, succinate dehydrogenase (SDH) catalyzes the oxidation of succinate and ubiquinone to fumarate and ubiquinol.N-Desethyl amodiaquine dihydrochloride Chemscene Four subunits comprise the SDH protein complex: a flavochrome subunit (SDHA), an iron-sulfur protein (SDHB) and two membrane-bound subunits (SDHC and SDHD) anchored to the inner mitochondrial membrane. Mutations to these subunits cause mitochondrial dysfunction, corresponding to several distinct disorders. Mutations in the membrane bound components may cause hereditary paraganglioma, while SDHA mutations associate with juvenile encephalopathy as well as Leigh syndrome, a severe neurological disorder. Inactivating mutations in SDHB correlate with inherited, but not necessarily sporadic, cases of pheochromocytoma.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Recombinant protein within human SDHB aa 100-280.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IF-Cell, IHC-P, FC
Coupling :
unconjugated
Clone number:
RRID:
AB_3069258
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.Price of m-PEG7-CH2CH2COOH Aliquot store at -20℃.PMID:33725156 Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 32 kDa
Positive control :
Wild-type Hela whole cell lysate, Rat liver tissue, human liver tissue, mouse liver tissue, 293T, HT-29, Hela, rat heart tissue, human liver tissue, human kidney tissue, human skin tissue, mouse colon tissue.