Product Name :
SFRP1 Mouse Monoclonal Antibody [4G04]
Predicted band size :
Observed band size :
Synonyms:
Frizzled related protein 1b antibody FRP 1b antibody FRP1b antibody SARP 3 antibody SARP3 antibody Secreted apoptosis related protein 3 antibody Secreted frizzled related protein 5 antibody SFRP 5 antibody
Function :
The frizzled gene was originally identified in Drosophila melanogaster and was shown to be involved in the development of tissue polarity. The mammalian homolog of frizzled, as well as several mammalian frizzled-related proteins, FRP-1 (also designated SARP2), FRP-2 (also designated SARP1), FRP-3 and SARP3 (also designated FRP-5) have been identified. Frizzled is a transmem- brane protein that functions as a receptor for Wnt. The frizzled related proteins FRP-1, FRP-2, FRP-3 and SARP3 are secreted proteins that contain regions of homology to the cysteine-rich ligand-binding domain of frizzled. The FRPs/ SARPs have also been shown to be involved in the Wnt signaling pathway by regulating the intracellular levels of β-catenin.
Antibody Type:
Mouse Monoclonal Antibody
Immunogen :
peptide
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IP, IF
Coupling :
unconjugated
Clone number:
4G04
RRID:
Form :
Liquid
Concentration :
2ug/ul
Storage instructions:
Store at +4℃
Storage buffer solution:
1.1083181-22-9 Chemscene 0 ml of PBS with
Subtype:
IgG1
Purification method :
Protein A affinity purified.Dihydro-2H-pyran-3(4H)-one Order
ELTSA :
Molecular weight :
40kDa
Positive control :
293T