Product Name :
Synaptotagmin 1 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
DKFZp781D2042 antibody FLJ42519 antibody p65 antibody SVP65 antibody Synaptotagmin 2 antibody Synaptotagmin I antibody Synaptotagmin II antibody Synaptotagmin-1 antibody SYT antibody Syt1 antibody 展开
Function :
May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca2+-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca2+-independent manner; these are neurexins, syntaxin and AP2. Plays a role in dendrite formation by melanocytes. The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin-1 participates in triggering neurotransmitter release at the synapse.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
KLH conjugated synthetic peptide derived from human Synaptotagmin 1 165-260/422
Species reactivity:
Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit
Verify application:
WB, ELISA, IHC-P, IF
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at -20℃ for one year.1,3,5-Tribromo-2,4,6-trimethylbenzene site Avoid repeated freeze/thaw cycles.Buy5-Amino-2-(4-aminophenyl)benzimidazole The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃.PMID:33430751 When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage buffer solution:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
48 KDa
Positive control :
Mouse Cerebrum Lysate, Mouse Cerebellum Lysate, Mouse Cerebral cortex Lysate, Rat Cerebrum Lysate.