Product Name :
Smad3 Mouse Monoclonal Antibody [8E1]
Predicted band size :
Observed band size :
Synonyms:
DKFZP586N0721 antibody DKFZp686J10186 antibody hMAD 3 antibody hMAD-3 antibody hSMAD3 antibody HSPC193 antibody HST17436 antibody JV15 2 antibody JV15-2 antibody JV152 antibody 展开
Function :
Smad proteins, the mammalian homologs of the Drosophila mothers against dpp (Mad) have been implicated as downstream effectors of TGFβ/BMP signaling.Smad1 (also designated Madr1 or JV4-1), Smad5 and mammalian Smad8 (also designated Smad9 or MadH6) are effectors of BMP-2 and BMP-4 function while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGFβ and Activin-mediated growth modulation. Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to Activin/TGFβ signaling by interfering with TGFβ-mediated phosphorylation of other Smad family members
Antibody Type:
Mouse Monoclonal Antibody
Immunogen :
peptide
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IP, IF, IHC-P
Coupling :
unconjugated
Clone number:
8E1
RRID:
Form :
Liquid
Concentration :
2ug/ul
Storage instructions:
Store at +4℃
Storage buffer solution:
1.Formula of 1220019-95-3 0 ml of PBS with
Subtype:
IgG1
Purification method :
Protein A affinity purified.2-Chloro-5-iodo-4-pyridinamine In stock
ELTSA :
Molecular weight :
54kDa
Positive control :
human tonsil tissue.PMID:33655854